Human Genotyping Array
- Genome-wide association studies (GWAS)
- Consumer genomic testing
- Polygenic risk scores
Overview
Human genotyping arrays are a robust and well-established tool for studies, such as validation, targeting common variants in large sample populations. Often used for genome-wide association studies (GWAS), arrays offer a high-throughput, cost-effective solution. Our arrays feature rapid data delivery with well-established analytical methods allowing for streamlined interpretation of results.
We use state-of-the-art Illumina array technologies including Infinium whole-genome genotyping and methylation arrays. Custom arrays provide flexible solutions to meet a range of study requirements. Proven array scanning systems image each array, helping researchers unravel the complex genetic architecture behind diseases. Additionally, in-house software SNP selection and analysis tools are used to optimize data precision and research scalability.
What’s Included
- Sample Receipt and Initial QC
- Microarray Analysis
- Bioinformatics Analysis
INPUT REQUIREMENTS
- Sample types include saliva, blood, buccal swabs, and formalin-fixed, paraffin-embedded (FFPE) samples.
- 200-250ng of DNA (20ng/µL)
- Fresh/frozen tissue and blood preferably yielding >500ng of DNA
Data Deliverable
- Data accessed via secure online digital transfer
MICROARRAY SERVICES
| Service | Utility | DNA Input | Total Markers |
|---|---|---|---|
| Infinium Asian Screening Array (ASA) | Comprehensive genome-wide coverage of East Asian populations for disease risk profiling, pharmacogenomics, wellness characterization, and complex disease discovery. | 200ng | 660,000 |
| Infinium Global Screening Array | Disease risk profiling, pharmacogenomics, wellness characterization, and complex disease discovery. s | 200ng | 654,027 |
| Infinium OncoArray | SNPs include genetic variants associated with breast, colorectal, lung, ovarian, and prostate cancers plus SNPs covering ancestry, quantitative traits, pharmacogenetics, and fine-mapping of common cancer susceptibility loci. | 200ng | 500,000 |
| Infinium PsychArray | SNPs include genetic variants associated with the research of common psychiatric conditions such as schizophrenia, bipolar disorder, autism spectrum disorders, attention deficit hyperactivity disorder, major depressive disorder, obsessive compulsive disorder, anorexia, and Tourette’s syndrome. | 200ng | 593,260 |
| Infinium MethylationEPIC | Quantitative interrogation of selected methylation sites across the genome, offering high-throughput research capabilities at a minimal cost per sample. | 250ng | 850,000 CpGs |